Reduced PAX2 expression in murine fallopian tube cells enhances estrogen receptor signaling

High-grade serous ovarian cancer (HGSOC) is thought to progress from a series of precursor lesions in the fallopian tube epithelium (FTE). One of the preneoplastic lesions found in the FTE is called a secretory cell outgrowth (SCOUT), which is partially defined by a loss of paired box 2 (PAX2). In t...

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Bibliografische gegevens
Gepubliceerd in:Carcinogenesis
Hoofdauteurs: Colina, Jose A, Varughese, Peter, Karthikeyan, Subbulakshmi, Salvi, Amrita, Modi, Dimple A, Burdette, Joanna E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Carcinogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350556/
https://ncbi.nlm.nih.gov/pubmed/31271204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz127
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