Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a chronic, food antigen–driven, inflammatory disease of the esophagus and is associated with impaired barrier function. Evidence is emerging that loss of esophageal expression of the serine peptidase inhibitor, kazal type 7 (SPINK7), is an upstream event in EoE path...

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Udgivet i:Sci Transl Med
Main Authors: Azouz, Nurit P., Klingler, Andrea M., Pathre, Purnima, Besse, John A., Baruch-Morgenstern, Netali Ben, Ballaban, Adina Y., Osswald, Garrett A., Brusilovsky, Michael, Habel, Jeff E., Caldwell, Julie M., Ynga-Durand, Mario A., Abonia, Pablo J., Hu, Yueh-Chiang, Wen, Ting, Rothenberg, Marc E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350155/
https://ncbi.nlm.nih.gov/pubmed/32461336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaz7773
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