Closo-Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy

One of the driving forces of carcinogenesis in humans is the aberrant activation of receptors; consequently, one of the most promising mechanisms for cancer treatment is receptor inhibition by chemotherapy. Although a variety of cancers are initially susceptible to chemotherapy, they eventually deve...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Couto, Marcos, Alamón, Catalina, García, María Fernanda, Kovacs, Mariángeles, Trias, Emiliano, Nievas, Susana, Pozzi, Emiliano, Curotto, Paula, Thorp, Silvia, Dagrosa, María Alejandra, Teixidor, Francesc, Viñas, Clara, Cerecetto, Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349914/
https://ncbi.nlm.nih.gov/pubmed/32517054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061408
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