High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor

Prostate cancer is the most commonly diagnosed malignancy in men. Its growth mainly relies on the activity of the androgen receptor (AR), justifying the use of androgen deprivation therapy as a gold standard treatment for the metastatic disease. Inhibition of the androgen axis using second generatio...

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Bibliografiska uppgifter
I publikationen:Cells
Huvudupphovsmän: Dellal, Hadjer, Boulahtouf, Abdelhay, Alaterre, Elina, Cuenant, Alice, Grimaldi, Marina, Bourguet, William, Gongora, Céline, Balaguer, Patrick, Pourquier, Philippe
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349874/
https://ncbi.nlm.nih.gov/pubmed/32560058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061469
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