Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T Cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T Cell Responses and Protect Mice against both Infections

Human adenoviruses (AdVs) are one of the most common causes of acute respiratory viral infections worldwide. Multiple AdV serotypes with low cross-reactivity circulate in the human population, making the development of an effective vaccine very challenging. In the current study, we designed a cross-...

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Détails bibliographiques
Publié dans:Vaccines (Basel)
Auteurs principaux: Isakova-Sivak, Irina, Matyushenko, Victoria, Stepanova, Ekaterina, Matushkina, Anastasia, Kotomina, Tatiana, Mezhenskaya, Daria, Prokopenko, Polina, Kudryavtsev, Igor, Kopeykin, Pavel, Sivak, Konstantin, Rudenko, Larisa
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349758/
https://ncbi.nlm.nih.gov/pubmed/32344618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8020196
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