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Universal Live-Attenuated Influenza Vaccine Candidates Expressing Multiple M2e Epitopes Protect Ferrets against a High-Dose Heterologous Virus Challenge

The development of an influenza vaccine with broad protection and durability remains an attractive idea due to the high mutation rate of the influenza virus. An extracellular domain of Matrix 2 protein (M2e) is among the most attractive target for the universal influenza vaccine owing to its high co...

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Библиографические подробности
Опубликовано в: :Viruses
Главные авторы: Mezhenskaya, Daria, Isakova-Sivak, Irina, Matyushenko, Victoria, Donina, Svetlana, Rekstin, Andrey, Sivak, Konstantin, Yakovlev, Kirill, Katelnikova, Anastasia, Kryshen, Kirill, Makarov, Valery, Rudenko, Larisa
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310119/
https://ncbi.nlm.nih.gov/pubmed/34209093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071280
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