Mismatch Repair Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy

PURPOSE: Evaluate response of mismatch repair deficient (dMMR) rectal cancer to neoadjuvant chemotherapy. PATIENTS AND METHODS: dMMR rectal tumors at Memorial Sloan Kettering were retrospectively reviewed for characteristics, treatment, and outcomes. Fifty dMMR rectal cancer patients were identified...

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Pubblicato in:Clin Cancer Res
Autori principali: Cercek, Andrea, Dos Santos Fernandes, Gustavo, Roxburgh, Campbell S. D., Ganesh, Karuna, Ng, Shu Y., Sanchez-Vega, Francisco, Yaeger, Rona, Segal, Neil H., Reidy-Lagunes, Diane L., Varghese, Anna, Markowitz, Arnold J., Wu, Chao, Szeglin, Bryan C., Sauve, Charles, Salo-Mullen, Erin, Tran, Christina, Patel, Zalak, Krishnan, Asha, Tkachuk, Kaitlyn, Nash, Garrett M., Guillem, Jose G., Paty, Philip B., Shia, Jinru, Schultz, Nikolaus, Garcia-Aguilar, Julio, Diaz, Luis A., Goodman, Karyn, Saltz, Leonard B., Weiser, Martin R., Smith, J. Joshua, Stadler, Zsofia K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348681/
https://ncbi.nlm.nih.gov/pubmed/32144135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3728
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