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Exendin‐4, a GLP‐1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia–reperfusion injury

BACKGROUND AND PURPOSE: The aim of this study is to investigate the vasorelaxant effect of exendin‐4, a GLP‐1 receptor agonist on retinal capillaries under normal and ischaemia–reperfusion (I/R) conditions. EXPERIMENTAL APPROACH: Capillary diameters in the whole‐mounted retina were directly observed...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhai, Ruyi, Xu, Huan, Hu, Fangyuan, Wu, Jihong, Kong, Xiangmei, Sun, Xinghuai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348095/
https://ncbi.nlm.nih.gov/pubmed/32232832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15059
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