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Exendin‐4, a GLP‐1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia–reperfusion injury

BACKGROUND AND PURPOSE: The aim of this study is to investigate the vasorelaxant effect of exendin‐4, a GLP‐1 receptor agonist on retinal capillaries under normal and ischaemia–reperfusion (I/R) conditions. EXPERIMENTAL APPROACH: Capillary diameters in the whole‐mounted retina were directly observed...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Zhai, Ruyi, Xu, Huan, Hu, Fangyuan, Wu, Jihong, Kong, Xiangmei, Sun, Xinghuai
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348095/
https://ncbi.nlm.nih.gov/pubmed/32232832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15059
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