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Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension

BACKGROUND AND PURPOSE: Pulmonary arterial hypertension (PAH, type 1 pulmonary hypertension) has a 3‐year survival of ~50% and is in need of new, effective therapies. In PAH, remodelling of the pulmonary artery (PA) increases pulmonary vascular resistance and can result in right heart dysfunction an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Gorr, Matthew W., Sriram, Krishna, Muthusamy, Abinaya, Insel, Paul A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348089/
https://ncbi.nlm.nih.gov/pubmed/32337710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15074
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