METTL3 Induces AAA Development and Progression by Modulating N6-Methyladenosine-Dependent Primary miR34a Processing

Identifying effective drugs to delay the progression of aortic aneurysms is a formidable challenge in vascular medicine. Methyltransferase-like 3 (METTL3) plays a key role in catalyzing the formation of N6-methyladenosine (m(6)A), but despite the functional importance of METTL3 and m(6)A in various...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhong, Lintao, He, Xiang, Song, Haoyu, Sun, Yili, Chen, Guojun, Si, Xiaoyun, Sun, Jie, Chen, Xiaoqiang, Liao, Wangjun, Liao, Yulin, Bin, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347714/
https://ncbi.nlm.nih.gov/pubmed/32650237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.06.005
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