Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The OX40-OX40L pathway provides crucial co-stimulatory signals for CD4 T cell responses, however the precise cellular interactions critical for OX40L provision in vivo and when these occur, remains unclear. Here, we demonstrate that provision of OX40L by dendritic cells (DCs), but not T cells, B cel...

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Vydáno v:Nat Commun
Hlavní autoři: Gajdasik, Dominika W., Gaspal, Fabrina, Halford, Emily E., Fiancette, Remi, Dutton, Emma E., Willis, Claire, Rückert, Timo, Romagnani, Chiara, Gerard, Audrey, Bevington, Sarah L., MacDonald, Andrew S., Botto, Marina, Vyse, Timothy, Withers, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347572/
https://ncbi.nlm.nih.gov/pubmed/32647184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17293-3
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