Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The OX40-OX40L pathway provides crucial co-stimulatory signals for CD4 T cell responses, however the precise cellular interactions critical for OX40L provision in vivo and when these occur, remains unclear. Here, we demonstrate that provision of OX40L by dendritic cells (DCs), but not T cells, B cel...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Gajdasik, Dominika W., Gaspal, Fabrina, Halford, Emily E., Fiancette, Remi, Dutton, Emma E., Willis, Claire, Rückert, Timo, Romagnani, Chiara, Gerard, Audrey, Bevington, Sarah L., MacDonald, Andrew S., Botto, Marina, Vyse, Timothy, Withers, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347572/
https://ncbi.nlm.nih.gov/pubmed/32647184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17293-3
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