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Analysis of tumor mutational burden: correlation of five large gene panels with whole exome sequencing
Outcome of immune checkpoint inhibition in cancer can be predicted by measuring PDL1 expression of tumor cells. Search for additional biomarkers led to tumor mutational burden (TMB) as surrogate marker for neoantigens presented. While TMB was previously determined via whole exome sequencing (WES), t...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347536/ https://ncbi.nlm.nih.gov/pubmed/32647293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68394-4 |
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