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Quantification of IDO1 enzyme activity in normal and malignant tissues
Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first and rate-limiting reaction of l-tryptophan (Trp) conversion into l-kynurenine (Kyn). The depletion of Trp, and the accumulation of Kyn have been proposed as mechanisms that contribute to the suppression of the immune response—primarily evidenc...
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| Vydáno v: | Methods Enzymol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347075/ https://ncbi.nlm.nih.gov/pubmed/31727243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.07.006 |
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