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Quantification of IDO1 enzyme activity in normal and malignant tissues

Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first and rate-limiting reaction of l-tryptophan (Trp) conversion into l-kynurenine (Kyn). The depletion of Trp, and the accumulation of Kyn have been proposed as mechanisms that contribute to the suppression of the immune response—primarily evidenc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Methods Enzymol
Egile Nagusiak: Zhai, Lijie, Ladomersky, Erik, Bell, April, Dussold, Corey, Cardoza, Krislyn, Qian, Jun, Lauing, Kristen L., Wainwright, Derek A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347075/
https://ncbi.nlm.nih.gov/pubmed/31727243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.07.006
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