A carregar...
Structural basis for allosteric PARP-1 retention on DNA breaks
INTRODUCTION: Poly(ADP-ribose) polymerase-1 (PARP-1) is an abundant enzyme in the cell nucleus that regulates genome repair by binding to DNA damage sites and creating the poly(ADP-ribose) posttranslational modification. PARP-1 hyperactivity leads to cell stress/death associated with many prominent...
Na minha lista:
| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347020/ https://ncbi.nlm.nih.gov/pubmed/32241924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax6367 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|