Prescription Opioids induce Gut Dysbiosis and Exacerbate Colitis in a Murine Model of Inflammatory Bowel Disease

BACKGROUND AND AIMS: Opioids are the most prescribed analgesics for pain in inflammatory bowel diseases [IBD]; however, the consequences of opioid use on IBD severity are not well defined. This is the first study investigating consequences of hydromorphone in both dextran sodium sulphate [DSS]-induc...

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Veröffentlicht in:J Crohns Colitis
Hauptverfasser: Sharma, Umakant, Olson, Rohini Khatri, Erhart, Federico Nicolas, Zhang, Li, Meng, Jingjing, Segura, Bradley, Banerjee, Santanu, Sharma, Madhulika, Saluja, Ashok Kumar, Ramakrishnan, Sundaram, Abreu, Maria T, Roy, Sabita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346895/
https://ncbi.nlm.nih.gov/pubmed/31773170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz188
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