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Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis

BACKGROUND: Ulcerative colitis (UC) is a Th2 inflammatory bowel disease characterized by increased IL-5 and IL-13 expression, eosinophilic/neutrophilic infiltration, decreased mucus production, impaired epithelial barrier, and bacterial dysbiosis of the colon. Acetylcholine and nicotine stimulate mu...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Singh, Shashi P., Chand, Hitendra S., Banerjee, Santanu, Agarwal, Hemant, Raizada, Veena, Roy, Sabita, Sopori, Mohan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943409/
https://ncbi.nlm.nih.gov/pubmed/31643033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-019-05838-6
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