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Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers

[Image: see text] Pathogenesis of Alzheimer’s disease (AD), the most common type of dementia, involves misfolding and aggregation of the extracellular amyloid-β (Aβ) protein where the intermediate oligomers, formed during the aggregation progression cascade, are considered the prime toxic species. H...

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Publicat a:ACS Omega
Autors principals: Bhattacharyya, Rajanya, Bhattacharjee, Sayan, Pathak, Bani K., Sengupta, Jayati
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346273/
https://ncbi.nlm.nih.gov/pubmed/32656435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01730
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