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Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2

Gab2 is a scaffold protein with a crucial role in colocalizing signaling proteins and it is involved in the regulation of several important molecular pathways. SHP2 is a protein phosphatase that binds, through its two SH2 domains, specific consensus sequences presenting a phosphorylated tyrosine loc...

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Detalhes bibliográficos
Publicado no:Life (Basel)
Main Authors: Visconti, Lorenzo, Malagrinò, Francesca, Pagano, Livia, Toto, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345789/
https://ncbi.nlm.nih.gov/pubmed/32545165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10060085
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