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Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro

Flucloxacillin (FLU), an isoxazolyl penicillin, is widely used for the treatment of different bacterial infections in intensive care units (ICU). Being highly bound to plasma proteins, FLU is prone to drug-drug interactions (DDI) when administered concurrently with other drugs. As FLU is binding to...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Stolte, Maximilian, Ali, Weaam, Jänis, Janne, Gessner, Andre’, El-Najjar, Nahed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345279/
https://ncbi.nlm.nih.gov/pubmed/32521723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9060309
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