Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro

Flucloxacillin (FLU), an isoxazolyl penicillin, is widely used for the treatment of different bacterial infections in intensive care units (ICU). Being highly bound to plasma proteins, FLU is prone to drug-drug interactions (DDI) when administered concurrently with other drugs. As FLU is binding to...

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Bibliografiska uppgifter
I publikationen:Antibiotics (Basel)
Huvudupphovsmän: Stolte, Maximilian, Ali, Weaam, Jänis, Janne, Gessner, Andre’, El-Najjar, Nahed
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345279/
https://ncbi.nlm.nih.gov/pubmed/32521723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9060309
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