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Copolymeric Micelles Overcome the Oral Delivery Challenges of Amphotericin B

Classified as a Biopharmaceutical Classification System (BCS) class IV drug, amphotericin B (AmB) has low aqueous solubility and low permeability leading to low oral bioavailability. To improve these limitations, this study investigated the potential of AmB-loaded polymeric micelles (AmB-PM) to incr...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Nimtrakul, Pataranapa, Williams, Desmond B., Tiyaboonchai, Waree, Prestidge, Clive A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344903/
https://ncbi.nlm.nih.gov/pubmed/32545189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13060121
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