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Strategies to enhance oral delivery of amphotericin B: a comparison of uncoated and enteric-coated nanostructured lipid carriers

The oral delivery of amphotericin B (AmB) has remained a challenge due to its low solubility, permeability, and instability in gastric acidic pH. To solve these issues, herein, we reported a novel approach of using nanostructured lipid carriers (NLCs) and NLCs coating with Eudragit(®)L100-55 (Eu-NLC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Nimtrakul, Pataranapa, Sermsappasuk, Pakawadee, Tiyaboonchai, Waree
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470155/
https://ncbi.nlm.nih.gov/pubmed/32633144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2020.1785050
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