Structural Modifications of 3-Triazeneindoles and Their Increased Activity Against Mycobacterium tuberculosis

We synthesized 100 novel indole-based compounds with polyaza-functionalities, including 3-triazeneindoles, and tested their activity in vitro against laboratory M. tuberculosis H37Rv and clinical izoniazid-resistant CN-40 isolates, using gross and fine titration approaches. Here we present a few 3-t...

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Bibliografiske detaljer
Udgivet i:Antibiotics (Basel)
Main Authors: Majorov, Konstantin B., Nikonenko, Boris V., Ivanov, Pavel Yu., Telegina, Lyudmila N., Apt, Alexander S., Velezheva, Valeria S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344711/
https://ncbi.nlm.nih.gov/pubmed/32599854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9060356
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