ROR1 is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells

The receptor tyrosine kinase ROR1 is absent in most normal adult tissues, but overexpressed in several malignancies. In this study, we explored clinical and functional inhibitory aspects of ROR1 in diffuse large B-cell lymphoma (DLBCL). ROR1 expression in tumor cells was more often observed in prima...

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Vydáno v:Biomedicines
Hlavní autoři: Ghaderi, Amineh, Daneshmanesh, Amir Hossein, Moshfegh, Ali, Kokhaei, Parviz, Vågberg, Jan, Schultz, Johan, Olin, Thomas, Harrysson, Sara, Smedby, Karin E, Drakos, Elias, Rassidakis, Georgios Z., Österborg, Anders, Mellstedt, Håkan, Hojjat-Farsangi, Mohammad
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344684/
https://ncbi.nlm.nih.gov/pubmed/32586008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8060170
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