Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy

Matrix metalloproteinases (MMPs) are a family of enzymes involved at different stages of cancer progression and metastasis. We previously identified a novel class of bisphosphonic inhibitors, selective for MMPs crucial for bone remodeling, such as MMP-2. Due to the increasing relevance of specific M...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Laghezza, Antonio, Piemontese, Luca, Brunetti, Leonardo, Caradonna, Alessia, Agamennone, Mariangela, Di Pizio, Antonella, Pochetti, Giorgio, Montanari, Roberta, Capelli, Davide, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344628/
https://ncbi.nlm.nih.gov/pubmed/32492898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13060113
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