Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

PPAR antagonists are ligands that bind their receptor with high affinity without transactivation activity. Recently, they have been demonstrated to maintain insulin-sensitizing and antidiabetic properties, and they serve as an alternative treatment for metabolic diseases. In this work, an affinity-b...

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Pubblicato in:Sci Rep
Autori principali: Brusotti, Gloria, Montanari, Roberta, Capelli, Davide, Cattaneo, Giulia, Laghezza, Antonio, Tortorella, Paolo, Loiodice, Fulvio, Peiretti, Franck, Bonardo, Bernadette, Paiardini, Alessandro, Calleri, Enrica, Pochetti, Giorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516003/
https://ncbi.nlm.nih.gov/pubmed/28720829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05666-6
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