Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

PPAR antagonists are ligands that bind their receptor with high affinity without transactivation activity. Recently, they have been demonstrated to maintain insulin-sensitizing and antidiabetic properties, and they serve as an alternative treatment for metabolic diseases. In this work, an affinity-b...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Brusotti, Gloria, Montanari, Roberta, Capelli, Davide, Cattaneo, Giulia, Laghezza, Antonio, Tortorella, Paolo, Loiodice, Fulvio, Peiretti, Franck, Bonardo, Bernadette, Paiardini, Alessandro, Calleri, Enrica, Pochetti, Giorgio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516003/
https://ncbi.nlm.nih.gov/pubmed/28720829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05666-6
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