Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

PPAR antagonists are ligands that bind their receptor with high affinity without transactivation activity. Recently, they have been demonstrated to maintain insulin-sensitizing and antidiabetic properties, and they serve as an alternative treatment for metabolic diseases. In this work, an affinity-b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brusotti, Gloria, Montanari, Roberta, Capelli, Davide, Cattaneo, Giulia, Laghezza, Antonio, Tortorella, Paolo, Loiodice, Fulvio, Peiretti, Franck, Bonardo, Bernadette, Paiardini, Alessandro, Calleri, Enrica, Pochetti, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516003/
https://ncbi.nlm.nih.gov/pubmed/28720829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05666-6
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