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A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents

ABSTRACT: As the KL-VS haplotype alters secretion and activity of KLOTHO and uric acid (UA) is associated with endothelial dysfunction and inflammation, their mutual links may contribute to microalbuminuria (MA) in patients with type 1 diabetes (T1D). Therefore, we hypothesize that KL-VS polymorphis...

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Bibliografiske detaljer
Udgivet i:J Mol Med (Berl)
Main Authors: Słomiński, Bartosz, Ryba-Stanisławowska, Monika, Skrzypkowska, Maria, Gabig-Cimińska, Magdalena, Myśliwiec, Małgorzata
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343757/
https://ncbi.nlm.nih.gov/pubmed/32435919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01918-7
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