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Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes

ABSTRACT: Wild-type TP53 plays an important role in the regulation of immune response and systemic inflammation. In type 1 diabetes (T1D), TP53 pathways are upregulated and an increased susceptibility to apoptosis is observed. We hypothesize that TP53 codon 72 polymorphism could be associated with c...

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Vydáno v:J Mol Med (Berl)
Hlavní autoři: Słomiński, Bartosz, Skrzypkowska, Maria, Ryba-Stanisławowska, Monika, Myśliwiec, Małgorzata, Trzonkowski, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055568/
https://ncbi.nlm.nih.gov/pubmed/33495869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-02035-1
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