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Elevated Levels of Serum IL-12 and IL-18 are Associated with Lower Frequencies of CD4(+)CD25(high)FOXP3(+) Regulatory T cells in Young Patients with Type 1 Diabetes

Type 1 diabetes is thought to involve chronic inflammation, which is manifested by the activation and expression of different inflammatory mediators. IL-12 and IL-18 are two cytokines that have been shown to exert strong proinflammatory activity and have been implicated in the pathogenesis of type 1...

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Autors principals: Ryba-Stanisławowska, Monika, Rybarczyk-Kapturska, Karolina, Myśliwiec, Małgorzata, Myśliwska, Jolanta
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174326/
https://ncbi.nlm.nih.gov/pubmed/24677179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-014-9878-1
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