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Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer

CD8(+) tumor-infiltrating lymphocytes (TILs) are not all specific for tumor antigens, but can include bystander TILs that are specific for cancer-irrelevant epitopes, and it is unknown whether the T-cell repertoire affects prognosis. To delineate the complexity of anti-tumor T-cell responses, we uti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tsuji, Takemasa, Eng, Kevin H., Matsuzaki, Junko, Battaglia, Sebastiano, Szender, J. Brian, Miliotto, Anthony, Gnjatic, Sacha, Bshara, Wiam, Morrison, Carl D., Lele, Shashikant, Emerson, Ryan O., Wang, Jianmin, Liu, Song, Robins, Harlan, Lugade, Amit A., Odunsi, Kunle
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343634/
https://ncbi.nlm.nih.gov/pubmed/32676168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27666
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