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Long noncoding RNA KCNQ1OT1 promotes colorectal carcinogenesis by enhancing aerobic glycolysis via hexokinase-2

In this study, we investigated the mechanistic role and prognostic significance of the long coding RNA (lncRNA) KCNQ1OT1 in colorectal cancer (CRC). KCNQ1OT1 levels were significantly higher in CRC tissues than adjacent normal colorectal tissues (n=79). High KCNQ1OT1 expression correlated with poore...

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Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Chen, Cheng, Wei, Meng, Wang, Chao, Sun, Danping, Liu, Peng, Zhong, Xin, Yu, Wenbin
Format: Artigo
Langue:Inglês
Publié: Impact Journals 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343465/
https://ncbi.nlm.nih.gov/pubmed/32564010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103334
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