Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture

Glucagon-like peptide-1 (GLP-1) from intestinal L-cells stimulates insulin secretion and reduces appetite after food ingestion, and it is the basis for drugs against type-2 diabetes and obesity. Drugs targeting L- and other enteroendocrine cells are under development, with the aim to mimic endocrine...

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Vydáno v:Cell Rep
Hlavní autoři: Goldspink, Deborah A., Lu, Van B., Miedzybrodzka, Emily L., Smith, Christopher A., Foreman, Rachel E., Billing, Lawrence J., Kay, Richard G., Reimann, Frank, Gribble, Fiona M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342002/
https://ncbi.nlm.nih.gov/pubmed/32610134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107833
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