Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis

Arabinosyltransferase B (EmbB) belongs to a family of membrane-bound glycosyltransferases that build the lipidated polysaccharides of the mycobacterial cell envelope, and are targets of anti-tuberculosis drug ethambutol. We present the 3.3 Å resolution single-particle cryo-electron microscopy struct...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tan, Yong Zi, Rodrigues, José, Keener, James E., Zheng, Ruixiang Blake, Brunton, Richard, Kloss, Brian, Giacometti, Sabrina I., Rosário, Ana L., Zhang, Lei, Niederweis, Michael, Clarke, Oliver B., Lowary, Todd L., Marty, Michael T., Archer, Margarida, Potter, Clinton S., Carragher, Bridget, Mancia, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341804/
https://ncbi.nlm.nih.gov/pubmed/32636380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17202-8
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