Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2)

Inhibition of Mycobacterium tuberculosis (Mtb) cell wall assembly is an established strategy for anti-TB chemotherapy. Arabinosyltransferase EmbB, which catalyzes the transfer of arabinose from the donor decaprenyl-phosphate-arabinose (DPA) to its arabinosyl acceptor is an essential enzyme for Mtb c...

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Vydáno v:Protein Cell
Hlavní autoři: Zhang, Lu, Zhao, Yao, Gao, Ruogu, Li, Jun, Yang, Xiuna, Gao, Yan, Zhao, Wei, Gurcha, Sudagar S., Veerapen, Natacha, Batt, Sarah M., Besra, Kajelle Kaur, Xu, Wenqing, Bi, Lijun, Zhang, Xian’en, Guddat, Luke W., Yang, Haitao, Wang, Quan, Besra, Gurdyal S., Rao, Zihe
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305291/
https://ncbi.nlm.nih.gov/pubmed/32363534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00726-6
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