Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer

SULT2B1b (SULT2B) is a prostate-expressed hydroxysteroid sulfotransferase, which may regulate intracrine androgen homeostasis by mediating 3β-sulfation of dehydroepiandrosterone (DHEA), the precursor for 5α-dihydrotestosterone (DHT) biosynthesis. The aldo-keto reductase (AKR)1C3 regulates androgen r...

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Dades bibliogràfiques
Publicat a:Endocrinology
Autors principals: Park, Sulgi, Song, Chung-Seog, Lin, Chun-Lin, Jiang, Shoulei, Osmulski, Pawel A, Wang, Chiou-Miin, Marck, Brett T, Matsumoto, Alvin M, Morrissey, Colm, Gaczynska, Maria E, Chen, Yidong, Mostaghel, Elahe A, Chatterjee, Bandana
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341717/
https://ncbi.nlm.nih.gov/pubmed/31894239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz042
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