A role for cell‐autocrine interleukin‐2 in regulatory T‐cell homeostasis

Activated T‐cells make both interleukin‐2 (IL2) and its high‐affinity receptor component CD25. Regulatory CD4 T‐cells (Treg cells) do not make IL2, and the IL2‐CD25 circuit is considered a paracrine circuit crucial in their generation and maintenance. Yet, all T‐cells are capable of making IL2 at so...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Immunology
Huvudupphovsmän: Chawla, Amanpreet Singh, Khalsa, Jasneet Kaur, Dhar, Atika, Gupta, Suman, Umar, Danish, Arimbasseri, Gopalakrishnan Aneeshkumar, Bal, Vineeta, George, Anna, Rath, Satyajit
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341549/
https://ncbi.nlm.nih.gov/pubmed/32187647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13194
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk