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A role for cell‐autocrine interleukin‐2 in regulatory T‐cell homeostasis
Activated T‐cells make both interleukin‐2 (IL2) and its high‐affinity receptor component CD25. Regulatory CD4 T‐cells (Treg cells) do not make IL2, and the IL2‐CD25 circuit is considered a paracrine circuit crucial in their generation and maintenance. Yet, all T‐cells are capable of making IL2 at so...
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| Publicado no: | Immunology |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7341549/ https://ncbi.nlm.nih.gov/pubmed/32187647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13194 |
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