Extensive Remodeling of the Immune Microenvironment in B-cell Acute Lymphoblastic Leukemia

A subset of B-cell acute lymphoblastic leukemia (B-ALL) patients will relapse and succumb to therapy-resistant disease. The bone marrow microenvironment may support B-ALL progression and treatment evasion. Utilizing single-cell approaches, we demonstrate B-ALL bone marrow immune microenvironment re-...

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Bibliografski detalji
Izdano u:Cancer Cell
Glavni autori: Witkowski, Matthew T., Dolgalev, Igor, Evensen, Nikki A., Ma, Chao, Chambers, Tiffany, Roberts, Kathryn G., Sreeram, Sheetal, Dai, Yuling, Tikhonova, Anastasia N., Lasry, Audrey, Qu, Chunxu, Pei, Deqing, Cheng, Cheng, Robbins, Gabriel A., Pierro, Joanna, Selvaraj, Shanmugapriya, Mezzano, Valeria, Daves, Maria, Lupo, Philip J., Scheurer, Michael E., Loomis, Cynthia A., Mullighan, Charles G., Chen, Weiqiang, Rabin, Karen R., Tsirigos, Aristotelis, Carroll, William L., Aifantis, Iannis
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341535/
https://ncbi.nlm.nih.gov/pubmed/32470390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.04.015
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