Extensive Remodeling of the Immune Microenvironment in B-cell Acute Lymphoblastic Leukemia

A subset of B-cell acute lymphoblastic leukemia (B-ALL) patients will relapse and succumb to therapy-resistant disease. The bone marrow microenvironment may support B-ALL progression and treatment evasion. Utilizing single-cell approaches, we demonstrate B-ALL bone marrow immune microenvironment re-...

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Publicado no:Cancer Cell
Main Authors: Witkowski, Matthew T., Dolgalev, Igor, Evensen, Nikki A., Ma, Chao, Chambers, Tiffany, Roberts, Kathryn G., Sreeram, Sheetal, Dai, Yuling, Tikhonova, Anastasia N., Lasry, Audrey, Qu, Chunxu, Pei, Deqing, Cheng, Cheng, Robbins, Gabriel A., Pierro, Joanna, Selvaraj, Shanmugapriya, Mezzano, Valeria, Daves, Maria, Lupo, Philip J., Scheurer, Michael E., Loomis, Cynthia A., Mullighan, Charles G., Chen, Weiqiang, Rabin, Karen R., Tsirigos, Aristotelis, Carroll, William L., Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341535/
https://ncbi.nlm.nih.gov/pubmed/32470390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.04.015
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