A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes

The unbalanced translocation dic(1;7)(q10;p10) in myelodysplastic syndromes (MDS) is originated by centromeric juxtaposition resulting into 1q trisomy and 7q monosomy. More than half of cases arise after chemo/radio-therapy. To date, given the absence of genes within the centromeric regions, no spec...

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書誌詳細
出版年:Leukemia
主要な著者: Fernandez, Anair Graciela Lema, Crescenzi, Barbara, Pierini, Valentina, Di Battista, Valeria, Barba, Gianluca, Pellanera, Fabrizia, Di Giacomo, Danika, Roti, Giovanni, Piazza, Rocco, Adelman, Emmalee R, Figueroa, Maria E, Mecucci, Cristina
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340798/
https://ncbi.nlm.nih.gov/pubmed/30923319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0433-9
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