Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells

Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy. This approach may still be limited by the presence of immunosuppressive myeloid populations. Here, we demonstrate that NK cells (haNKs) enginee...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Robbins, Yvette, Greene, Sarah, Friedman, Jay, Clavijo, Paul E, Van Waes, Carter, Fabian, Kellsye P, Padget, Michelle R, Abdul Sater, Houssein, Lee, John H, Soon-Shiong, Patrick, Gulley, James, Schlom, Jeffrey, Hodge, James W, Allen, Clint T
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340502/
https://ncbi.nlm.nih.gov/pubmed/32633234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54854
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