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Aberrant sorting of hippocampal complex pyramidal cells in type I lissencephaly alters topological innervation

Layering has been a long-appreciated feature of higher order mammalian brain structures but the extent to which it plays an instructive role in synaptic specification remains unknown. Here we examine the formation of synaptic circuitry under cellular heterotopia in hippocampal CA1, using a mouse mod...

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Pubblicato in:eLife
Autori principali: D'Amour, James A, Ekins, Tyler, Ganatra, Stuti, Yuan, Xiaoqing, McBain, Chris J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340499/
https://ncbi.nlm.nih.gov/pubmed/32558643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55173
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