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Adaptive optics for a time-resolved Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM) in vivo

Förster resonance energy transfer (FRET) and fluorescence lifetime imaging (FLIM) have been coupled with multiphoton microscopy to image in vivo dynamics. However, the increase in optical aberrations as a function of depth significantly reduces the fluorescent signal, spatial resolution, and fluores...

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Detalhes bibliográficos
Publicado no:Opt Lett
Main Authors: Coelho, Simao, Poland, Simon P., Devauges, Viviane, Ameer-Beg, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340371/
https://ncbi.nlm.nih.gov/pubmed/32412453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/OL.385950
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