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The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae
The S. cerevisiae ISR1 gene encodes a putative kinase with no ascribed function. Here, we show that Isr1 acts as a negative regulator of the highly-conserved hexosamine biosynthesis pathway (HBP), which converts glucose into uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), the carbohydrate prec...
Gorde:
| Argitaratua izan da: | PLoS Genet |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7340321/ https://ncbi.nlm.nih.gov/pubmed/32579556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008840 |
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