Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in Francisella tularensis

Host-derived glutathione (GSH) is an essential source of cysteine for the intracellular pathogen Francisella tularensis. In a comprehensive transposon insertion sequencing screen, we identified several F. tularensis genes that play central and previously unappreciated roles in the utilization of GSH...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Ramsey, Kathryn M., Ledvina, Hannah E., Tresko, Tenayaann M., Wandzilak, Jamie M., Tower, Catherine A., Tallo, Thomas, Schramm, Caroline E., Peterson, S. Brook, Skerrett, Shawn J., Mougous, Joseph D., Dove, Simon L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340319/
https://ncbi.nlm.nih.gov/pubmed/32492066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008566
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