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A response regulator promotes Francisella tularensis intramacrophage growth by repressing an anti-virulence factor

The orphan response regulator PmrA is essential for the intramacrophage growth and survival of Francisella tularensis. PmrA was thought to promote intramacrophage growth by binding directly to promoters on the Francisella Pathogenicity Island (FPI) and positively regulating the expression of FPI gen...

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Bibliographic Details
Published in:Mol Microbiol
Main Authors: Ramsey, Kathryn M., Dove, Simon L.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020902/
https://ncbi.nlm.nih.gov/pubmed/27169554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13418
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